TheraPHIX™, vivoPHIX™, genoPHIX™ and virusPHIX™

Next generation biosample stabilization

Our flagship stabilization solutions — TheraPHIX™, vivoPHIX™, genoPHIX™, virusPHIX™ and virusPHIX-P9™ — are designed for a wide range of applications within the life sciences. vivoPHIX™ leverages advanced molecular stabilization technology to ensure sample integrity during tissue fixation, dissociation, and single-cell workflows, including scRNA-seq and CITE-seq. virusPHIX™ facilitates virus inactivation and secure transport, preserving molecular fidelity for improved diagnostic accuracy and high-quality data generation.

For mRNA-LNP vaccine and therapeutic thermostabilization, please click here to learn more about TheraPHIX™.

Fixation Before Dissociation Using a Deep Eutectic Solvent Preserves In Vivo States and Phospho-Signaling in Single-Cell Sequencing

Single-cell RNA sequencing presents an opportunity to deconstruct cellular networks but is limited by the loss of biological information. In this study, a new method of fixation before dissociation using a deep eutectic solvent (DES) is presented.

This method enables multiple domains of in vivo biological data, including morphology, RNA, proteins and posttranslational modifications to be preserved.


The study demonstrates how deep eutectic based fixatives will allow the accurate reconstruction of in vivo cellular networks and uncover links between intracellular pathways.

"Very impressed by results"

Pasteur Institute

"It’s working amazingly for my project"

Sanger Institute

"The signals are very good"

University of Cambridge

"RNAssist samples have more reads per cell ... single cell libraries are better with RNAssist than without"

Sanger Institute

"I think the RNAssist is an amazing technology with important applications for us. And the results are quite amazing"

University of Calgary

"What I am seeing is that RNA quality is very high. The quality was higher than the corresponding methanol fixed tumour"

University of Oxford

"We have beautiful results in histopathology and similar beautiful IHC"

CFIA

"I can tell you that RNAssist is very good for storage of fixed tissue samples and further histological staining with hematoxilin and Eosin"

University of Rome
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Core features of our technology

TheraPHIX™, vivoPHIX™, genoPHIX™ and virusPHIX™ are patented, universal clinical sample stabilization and inactivation reagents with variously proven Research Use Only (RUO) and diagnostics applications including cell and tissue fixation, ISH, IF, tissue dissociation, scRNA-seq, NGS, viral transport, RT-PCR and Lateral Flow rapid tests

Cell and Tissue Fixation

  • Cellular morphology of fresh & fresh frozen tissue is conserved

  • Samples can be embedded in paraffin for staining

  • Compatible with GFP detection, IF, IHC, ISH H&E and RNAscope imaging

RNA, Protein and DNA Stablization

  • Long-term biomolecule stabilisation

  • Substantially improves RNA and DNA quality compared to competing products

  • Compatible with front-end RNA purification kits even when the sample is blood

Tissue Dissociation

  • Easy non-protease dissociation into individual cells retaining original 3D morphological characteristics with scRNAseq compatibility

  • Ready-to-use protocol for single-cell RNA-seq

  • Can be used for 16S NGS and WTA metagenomics

Virus Inactivation, Bacteria /Fungi/Parasite Killing Tests

  • Inactivates viruses, bacteria & yeast

  • Easy storage & transportation of sensitive samples

  • Stabilises HCV RNA for at least 12 months and SARS-CoV-2 RNA for least 6 weeks at 20°C

Safe Handling

  • Very low toxicity, non-flammable, non-crosslinking

  • No hood : carcinogen-free & low volatility reagent unlike formaldehyde

  • Partially biodegradable

  • Room temperature use

virusPHIX™ Virus Transport Media, SARS-CoV-2 inactivation, RNA and Antigen Stabilisation

  • Improves biosafety and logistics when transporting Covid-19 samples

  • Protects samples from excessive heat damage

  • Works with both swabs and saliva for Nucleic Acid and Antigen testing

Join the RNAssist Community - with 300+ evaluators worldwide

TheraPHIX™, vivoPHIX™, genoPHIX™, virusPHIX™ and virusPHIX-P9™ are patented next generation cell and tissue fixatives, biomolecule stabilisers with powerful virus and bacterial inactivation properties.

Our reagents are universally compatible with all sample types including viruses, bacteria, fungi, parasites, plants and animal cells and tissues. Both liquid and solid samples are rapidly and completely rendered fixed, stabilised and inactivated.


RNAssist technology supports a wide range of life science applications, including tissue fixation and dissociation, single-cell multiomics (scRNA-seq, CITE-seq), and virus inactivation and transport for enhanced diagnostic testing.

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